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Promoter region in prokaryotes

The promoter region has been highly conserved amongst eukaryotes and prokaryotes. This means that even distantly related organisms can share a very similar promoter sequence.

In prokaryotes, the promoter contains two sequences that are important for transcription. Prokaryotes have just one type of RNA polymerase which is able to transcribe all genes.

  • The TATAAT box, which is positioned around 10 bases away from the gene, allows RNA polymerase to bind to the DNA.

  • Around 35 bases away from the gene is a sequence of seven nucleotides TTGACTAT, which alters the rate of transcription.

Transcription factors bound to the promoter region.
Transcription factors bound to the promoter region.