The prokaryotic genome is far simpler than the eukaryotic genome.
The prokaryotic genome usually consists of a single circular chromosome. It may contain additional independently replicating strands. These strands are called plasmids.
The prokaryotic genome is much smaller than the eukaryotic genome. This is partly explained by the fact that it carries fewer genes, but is mainly because it has far less non-coding DNA.
The majority of prokaryotic chromosomes lack structural features that are universal in eukaryotes, including telomeres, centromeres and introns.
Bacterial chromosomes also lack histones and use a different method to condense their DNA.