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Comparison of bacterial and eukaryotic chromosomes

The bacterial chromosome has distinct features and is very different from the eukaryotic chromosome.

The bacterial chromosome is circular (rather than linear), has a single origin of replication and lacks structural proteins called histones (proteins that fold eukaryotic DNA).

The bacterial chromosome is sometimes said to not be a "true chromosome" because it lacks so many of the features that are characteristic of a eukaryotic chromosome.

The human genome on the left contains several linear chromosomes. The prokaryotic genome is organized as one large loop.
The human genome on the left contains several linear chromosomes. The prokaryotic genome is organized as one large loop.